Thursday, 20 September, 2018

First Trial Of Once-Daily Male Birth Control Pills Deemed A Success

Male contraceptive pill on the horizon Male contraceptive pill on the horizon Credit Paul Grover
Judith Alexander | 20 March, 2018, 04:47

The tests did not show whether taking the male birth control drug actually reduced sperm production to levels that would prevent pregnancy, but contraceptive effectiveness will be tested in another trial beginning in April, Fox News reported.

"Many men say they would prefer a daily pill as a reversible contraceptive, rather than long-acting injections or topical gels, which are also in development", Stephanie Page, the study's lead investigator, said in a press release. What about side effects? DMAU is being developed by the National Institutes of Health, Eunice Kennedy Shriver National Institute of Child Health and Human Development, which funded this study.

The idea of contraceptive pills for men has been floating about for some time now. According to University of Washington researchers, subjects didn't report any major symptoms or ill effects.

This recent study for a once-daily pill for men was carried out with groups in Washington and California.

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The results of the study, carried out with the help of Harbor-UCLA Medical Centre, were presented at ENDO 2018, the Endocrine Society's 100th annual meeting in Chicago.

This new pill has overcome some previous challenges facing male birth control, like damage to the liver and other parts of the body.

It is yet to be seen whether the drug proves to be a safe, effective contraceptive over long-term usage. It's 99 per cent effective when taken perfectly, Planned Parenthood wrote, but added that it's hard to do this. Similarly, Sheffield University professor of andrology Allan Pacey remarked that a "large randomized controlled trial" would be necessary to better test the male contraceptive's safety and efficacy, though he also acknowledged that the results "provide some hope" in the search for an effective oral contraceptive for men. The team is now currently working on developing a second compound to block the other sperm-transporting protein with a goal of bringing a hormone-free, reversible male pill to the general public within ten years. "Testosterone production is blocked and therefore sperm are not able to finish their last stages of maturation", she said.

"There has been very nice work in this area demonstrating that men across the globe - various races, ethnicities and across socioeconomic groups - are actually very interested in contraception", she added. Oral contraceptives are one of the medications most often used by Canadian women. They also said that these forms of the hormone also tend to clear too fast for the pills to work if taken only once per day, so two doses were needed.

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